Human APP Protein, His Tag (active enzyme, MALS verified), Unconjugated
Artikelnummer:
ABS-APP-H52H3-500UG
Hersteller Artikelnummer:
APP-H52H3-500ug
Alternativnummer:
ABS-APP-H52H3-500UG
Hersteller:
AcroBiosystems
Wirt:
Human
Kategorie:
Proteine/Peptide
Spezies Reaktivität:
Human
Konjugation:
Unconjugated
Amyloid precursor protein (APP) is a type I integral membrane protein ubiquitously expressed in many tissues and concentrated in the synapses of neurons. The majority of APP is cleaved at the plasma membrane by the alphasecretase in the nonamyloidogenic pathway. The amyloidogenic pathway starts with betasecretase cleavage by BACE1 on the Nterminal part of the Abeta domain, releasing sAPPbeta from a membraneanchored fragment named betaCTF or C103, which is subsequently cleaved by gammasecretase to release Abeta. - Proteine/Peptide
