Biotinylated Human B7-H6 / NCR3LG1 Protein, His,Avitag(TM)

Produktübersicht

• Artikelname: Biotinylated Human B7-H6 / NCR3LG1 Protein, His,Avitag(TM)
• Artikelnummer: ABS-B76-H82E5-200UG
• Hersteller Artikelnummer: B76-H82E5-200ug
• Alternativnummer: ABS-B76-H82E5-200UG
• Hersteller: AcroBiosystems
• Wirt: Human
• Kategorie: Proteine/Peptide
• Spezies Reaktivität: Human
• Konjugation: Biotin

Produktbeschreibung

The B7 family of genes is essential in the regulation of the adaptive immune system. one of which is the recently discovered B7H6. Humans and rats have a single B7H6 gene, however, many B7H6 genes were detected in a single large cluster in the Xenopus genome. Chimeric antigen receptor (CAR) Tcell therapies have demonstrated durable and potentially curative therapeutic efficacy against Bcell leukemia in clinical trials. In this study, B7H6, a ligand for the NK cell activating receptor NKp30, was targeted to create a CAR that targets multiple tumor types. B7H6 is expressed on various primary human tumors, including leukemia, lymphoma and gastrointestinal stromal tumors, but it is not constitutively expressed on normal tissues. - Proteine/Peptide

Produkteigenschaften

• Molekulargewicht: 30.4 kDa
• Tag: C-10*His & C-Avi
• NCBI: 68
• Puffer: PBS, pH7.4
• Reinheit: 90%
• Formulierung: Powder
• Target-Kategorie: B7-H6

Bilder

Immobilized Biotinylated Human B7-H6, His,Avitag (Cat. No. B76-H82E5) at 1 µg/mL (100 µL/well) on streptavidin (Cat. No. STN-N5116) precoated (0.5 µg/well) plate can bind Human NKp30, Fc Tag (Cat. No. NC3-H5259) with a linear range of 0.2-2 ng/mL (Routinely tested).

Biotinylated Human B7-H6, His,Avitag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.

B76-H82E5-200ug