Human BAFFR / TNFRSF13C Protein, Fc Tag (MALS verified), Unconjugated

Artikelnummer: ABS-BAR-H5253-1MG
Artikelname: Human BAFFR / TNFRSF13C Protein, Fc Tag (MALS verified), Unconjugated
Artikelnummer: ABS-BAR-H5253-1MG
Hersteller Artikelnummer: BAR-H5253-1mg
Alternativnummer: ABS-BAR-H5253-1MG
Hersteller: AcroBiosystems
Wirt: Human
Kategorie: Proteine/Peptide
Spezies Reaktivität: Human
Konjugation: Unconjugated
BAFF receptor (Bcell activating factor receptor, BAFFR), also known as tumor necrosis factor receptor superfamily member 13C (TNFRSF13C), is a membrane protein of the TNF receptor superfamily which recognizes BAFF. Bcell activating factor (BAFF) enhances Bcell survival in vitro and is a regulator of the peripheral Bcell population. Overexpression of BAFF in mice results in mature Bcell hyperplasia and symptoms of systemic lupus erythematosus (SLE). Also, some SLE patients have increased levels of BAFF in serum. Therefore, it has been proposed that abnormally high levels of BAFF may contribute to the pathogenesis of autoimmune diseases by enhancing the survival of autoreactive B cells. - Proteine/Peptide
Molekulargewicht: 33.1 kDa
Tag: C-Fc
NCBI: 96
Puffer: PBS, pH7.4
Reinheit: 95%
Formulierung: Powder
Target-Kategorie: BAFFR
Immobilized Human BAFF, His Tag (Cat. No. BAF-H5248) at 5 µg/mL (100 µL/well) can bind Human BAFFR Protein, Fc Tag (Cat. No. BAR-H5253) with a linear range of 0.2-4 ng/mL (QC tested).
Immobilized Human BAFFR Protein, Fc Tag (Cat. No. BAR-H5253) at 1 µg/mL (100 µL/well) can bind Anti-BAFFR Antibody, Human IgG1 with a linear range of 0.1-2 ng/mL (Routinely tested).
Human BAFFR Protein, Fc Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.