Mouse BAFFR / TNFRSF13C Protein, Fc Tag (MALS verified), Unconjugated, Human
Artikelnummer:
ABS-BAR-M5259-100UG
Hersteller Artikelnummer:
BAR-M5259-100ug
Alternativnummer:
ABS-BAR-M5259-100UG
Hersteller:
AcroBiosystems
Wirt:
Human
Kategorie:
Proteine/Peptide
Spezies Reaktivität:
Mouse
Konjugation:
Unconjugated
BAFF receptor (Bcell activating factor receptor, BAFFR), also known as tumor necrosis factor receptor superfamily member 13C (TNFRSF13C), is a membrane protein of the TNF receptor superfamily which recognizes BAFF. Bcell activating factor (BAFF) enhances Bcell survival in vitro and is a regulator of the peripheral Bcell population. Overexpression of BAFF in mice results in mature Bcell hyperplasia and symptoms of systemic lupus erythematosus (SLE). Also, some SLE patients have increased levels of BAFF in serum. Therefore, it has been proposed that abnormally high levels of BAFF may contribute to the pathogenesis of autoimmune diseases by enhancing the survival of autoreactive B cells. - Proteine/Peptide
Immobilized Mouse BAFF, Mouse IgG2a Fc Tag, low endotoxin (Cat. No. BAF-M5257) at 2 µg/mL (100 µL/well) can bind Mouse BAFFR, Fc Tag (Cat. No. BAR-M5259) with a linear range of 0.4-3 ng/mL (QC tested).
Mouse BAFFR, Fc Tag on SDS-PAGE under reducing (R) and under non-reducing (NR) conditions. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.
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