Anti-BCMA Neutralizing Antibody, Mouse IgG1 (recommended for neutralizing assay), Unconjugated, Human

Artikelnummer: ABS-BCA-M43-100UG
Artikelname: Anti-BCMA Neutralizing Antibody, Mouse IgG1 (recommended for neutralizing assay), Unconjugated, Human
Artikelnummer: ABS-BCA-M43-100UG
Hersteller Artikelnummer: BCA-M43-100ug
Alternativnummer: ABS-BCA-M43-100UG
Hersteller: AcroBiosystems
Wirt: Human
Kategorie: Antikörper
Spezies Reaktivität: Mouse
Konjugation: Unconjugated
Tumor necrosis factor receptor superfamily member 17 (TNFRSF17) is also known as Bcell maturation protein (BCMA), CD antigen CD269, which is a member of the TNFreceptor superfamily. TNFRSF17 contains one TNFRCys repeat. TNFRSF17 is expressed in mature Bcells, but not in Tcells or monocytes. TNFRSF17 is receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL. TNFRSF17 promotes Bcell survival and plays a role in the regulation of humoral immunity. TNFRSF17 can activate NFkappaB and JNK. - Antikörper
Tag: Mouse IgG1 | Mouse Kappa
Puffer: Tris with Glycine, Arginine and NaCl, pH7.5
Reinheit: 0.95
Formulierung: Powder
Target-Kategorie: BCMA
Immobilized Human BCMA Protein, His Tag (Cat. No. BCA-H522y) at 2 µg/mL (100 µL/well) can bind Anti-BCMA Neutralizing Antibody, Mouse IgG1 (Cat. No. BCA-M43) with a linear range of 0.2-6 ng/mL (QC tested).
Immobilized Human BCMA, His Tag (Cat. No. BCA-H522y) at 2 µg/mL (100 µL/well) can bind pre-mixed increasing concentrations of Anti-BCMA Neutralizing Antibody, Mouse IgG1 (Clone: AM43, Cat. No. BCA-M43) and 0.05 µg/mL (100 µL/well) Biotinylated Human APRIL, Fc,Avitag (Cat. No. APL-H82F5) with a half maximal inhibitory concentration (IC50) of 17.03 µg/mL (Routinely tested).
Anti-BCMA Neutralizing Antibody, Mouse IgG1 on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 0.95.
BCA-M43-100ug