Human Complement C5a Protein, His Tag, Unconjugated, E. coli

Produktübersicht

• Artikelname: Human Complement C5a Protein, His Tag, Unconjugated, E. coli
• Artikelnummer: ABS-C5A-H51H9-50UG
• Hersteller Artikelnummer: C5A-H51H9-50ug
• Alternativnummer: ABS-C5A-H51H9-50UG
• Hersteller: AcroBiosystems
• Wirt: E. coli
• Kategorie: Proteine/Peptide
• Spezies Reaktivität: Human
• Konjugation: Unconjugated

Produktbeschreibung

Complement Component C5a (C5a) is also known as C5,and is a protein fragment released from complement component C5.,is a potent chemotactic factor for human peripheral blood neutrophils and monocytes, and is believed to play an important role in a number of inflammatory conditions. There are several functions in the below: C5a is an anaphylatoxin, causing the release of histamine from mast cells, C5a is effective leukocyte chemoattractants, causing the accumulation of white blood cells, especially neutrophil granulocytes, at sites of complement activation, C5a activates white blood cells by increasing avidity for white blood cell integrins and upregulating the Lipoxygenase pathway for arachidonic acid metabolism, C5a is a powerful inflammatory mediator, and seems to be a key factor in the development of pathology of many inflammatory diseases involving the complement system, C5a modulates balance between activating versus inhibitory IgG Fc receptors on leukocytes, thereby enhancing autoimmune response. - Proteine/Peptide

Produkteigenschaften

• Molekulargewicht: 10.2 kDa
• Tag: N-10*His
• NCBI: 01031
• Puffer: PBS, pH7.4
• Reinheit: 95%
• Formulierung: Powder
• Target-Kategorie: Complement C5a

Bilder

Immobilized Human Complement C5a, His Tag (Cat. No. C5A-H51H9) at 5 µg/mL (100 µL/well) can bind Monoclonal Anti-Human C5a Human Antibody, Human IgG1 with a linear range of 0.1-4 ng/ml (QC tested).

Human Complement C5a, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.