Human CADM1 / IGSF4A Protein, His Tag, Unconjugated
Artikelnummer:
ABS-CA1-H5225-1MG
Hersteller Artikelnummer:
CA1-H5225-1mg
Alternativnummer:
ABS-CA1-H5225-1MG
Hersteller:
AcroBiosystems
Wirt:
Human
Kategorie:
Proteine/Peptide
Spezies Reaktivität:
Human
Konjugation:
Unconjugated
Cell Adhesion Molecules (CAMs) are proteins located on the cell surface involved with the binding with other cells or with the extracellular matrix (ECM) in the process called cell adhesion. Cell adhesion molecule 1 is a singlepass type I membrane protein which belongs to the nectin family. Cell Adhesion Molecule 1 contains two Iglike C2type (immunoglobulinlike) domains and one Iglike Vtype (immunoglobulinlike) domain, and is also known as CADM1, BL2, DKFZp686F1789, IGSF4, IGSF4A, MGC149785, MGC51880, NECL2, Necl2, RA175, ST17, SYNCAM, TSLC1, sTSLC1, sgIGSF, synCAM1. CADM1 mediates heterophilic cellcell adhesion with CADM3 and PVRL3 in a Ca2+independent manner. CADM1 acts as a tumor suppressor in nonsmallcell lung cancer (NSCLC) cells. CADM1 may be involved in neuronal migration, axon growth, pathfinding, and fasciculation on the axons of differentiating neurons. CADM1 may play diverse roles in the spermatogenesis including in the adhesion of spermatocytes and spermatids to Sertoli cells and for their normal differentiation into mature spermatozoa. - Proteine/Peptide
