Mouse Cadherin-3 Protein, His Tag, Unconjugated, Human
Artikelnummer:
ABS-CA3-M52H3-1MG
Hersteller Artikelnummer:
CA3-M52H3-1mg
Alternativnummer:
ABS-CA3-M52H3-1MG
Hersteller:
AcroBiosystems
Wirt:
Human
Kategorie:
Proteine/Peptide
Spezies Reaktivität:
Mouse
Konjugation:
Unconjugated
Cadherin3 (CDH3), also known as PCadherin, is a classical cadherin that functions as a calciumdependent glycoprotein mediating cellcell adhesion. Structurally, it is characterized by five extracellular cadherin repeats, a single transmembrane domain, and a highly conserved cytoplasmic tail. The CDH3 gene resides within a cadherin cluster on chromosome 16q, a genomic region linked to loss of heterozygosity in breast and prostate cancer. Furthermore, aberrant expression of the protein is implicated in the pathology of cervical adenocarcinoma. - Proteine/Peptide