Human Carbonic Anhydrase IX / CA9 (38-414) Protein, His Tag (active enzyme, MALS verified), Unconjugated
Artikelnummer:
ABS-CA9-H5226-50UG
Hersteller Artikelnummer:
CA9-H5226-50ug
Alternativnummer:
ABS-CA9-H5226-50UG
Hersteller:
AcroBiosystems
Wirt:
Human
Kategorie:
Proteine/Peptide
Spezies Reaktivität:
Human
Konjugation:
Unconjugated
Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes. CAs form a family of enzymes that catalyze the rapid interconversion of carbon dioxide and water to bicarbonate and protons (or vice versa), a reversible reaction that occurs rather slowly in the absence of a catalyst. One of the functions of the enzyme in animals is to interconvert carbon dioxide and bicarbonate to maintain acidbase balance in blood and other tissues, and to help transport carbon dioxide out of tissues. The active site of most carbonic anhydrases contains a zinc ion. There are at least five distinct CA families (alpha, beta, gamma, delta and epsilon). Carbonic anhydrase 9 (CA9 / CAIX) is also known as Membrane antigen MN (MN), Renal cell carcinomaassociated antigen G250, which belongs to the alphacarbonic anhydrase family. CA9 / CAIX with an optimal activity at pH 6.49. Reversible hydration of carbon dioxide. CA IX participates in pH regulation. CA9 may be involved in the control of cell proliferation and transformation. CAIX appears to be a novel specific biomarker for a cervical neoplasia. - Proteine/Peptide
