Human Cathepsin C Protein, His Tag (MALS verified), Unconjugated 50 ug

Produktübersicht

• Artikelname: Human Cathepsin C Protein, His Tag (MALS verified), Unconjugated 50 ug
• Artikelnummer: ABS-CAC-H52H3-50UG
• Hersteller Artikelnummer: CAC-H52H3-50ug
• Alternativnummer: ABS-CAC-H52H3-50UG
• Hersteller: AcroBiosystems
• Wirt: Human
• Kategorie: Proteine/Peptide
• Spezies Reaktivität: Human
• Konjugation: Unconjugated

Produktbeschreibung

This gene encodes a member of the peptidase C1 family and lysosomal cysteine proteinase that appears to be a central coordinator for activation of many serine proteinases in cells of the immune system. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate heavy and light chains that form a disulfidelinked dimer. A portion of the propeptide acts as an intramolecular chaperone for the folding and stabilization of the mature enzyme. This enzyme requires chloride ions for activity and can degrade glucagon. Defects in the encoded protein have been shown to be a cause of PapillonLefevre syndrome, an autosomal recessive disorder characterized by palmoplantar keratosis and periodontitis. [provided by RefSeq, Nov 2015] - Proteine/Peptide

Produkteigenschaften

• Molekulargewicht: 51.4 kDa
• Tag: C-10*His
• NCBI: 53634
• Puffer: 12.5 mM MES, 75 mM NaCl, pH6.5
• Reinheit: 95%
• Formulierung: Liquid
• Target-Kategorie: Cathepsin C

Bilder

Human Cathepsin C Protein, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.