Human CCR7 Full Length Protein (VLP), Unconjugated
Artikelnummer:
ABS-CC7-H52P3-500UG
Hersteller Artikelnummer:
CC7-H52P3-500ug
Alternativnummer:
ABS-CC7-H52P3-500UG
Hersteller:
AcroBiosystems
Wirt:
Human
Kategorie:
Proteine/Peptide
Spezies Reaktivität:
Human
Konjugation:
Unconjugated
The monoclonal antibody mAb729 reacts with the human CC chemokine receptor, CCR7. The protein encoded by this gene is a member of the G proteincoupled receptor family. This receptor was identified as a gene induced by the EpsteinBarr virus (EBV),and is thought to be a mediator of EBV effects on B lymphocytes. This receptor is expressed in various lymphoid tissues and activates B and T lymphocytes. It has been shown to control the migration of memory T cells to inflamed tissues, as well as stimulate dendritic cell maturation. The chemokine (CC motif) ligand 19 (CCL19/ECL) has been reported to be a specific ligand of this receptor. Signals mediated by this receptor regulate T cell homeostasis in lymph nodes, and may also function in the activation and polarization of T cells, and in chronic inflammation pathogenesis. - Proteine/Peptide
