Human Nectin-2 / CD112 Protein, Mouse IgG2a Fc Tag, Unconjugated

Artikelnummer: ABS-CD2-H5257-100UG
Artikelname: Human Nectin-2 / CD112 Protein, Mouse IgG2a Fc Tag, Unconjugated
Artikelnummer: ABS-CD2-H5257-100UG
Hersteller Artikelnummer: CD2-H5257-100ug
Alternativnummer: ABS-CD2-H5257-100UG
Hersteller: AcroBiosystems
Wirt: Human
Kategorie: Proteine/Peptide
Spezies Reaktivität: Human
Konjugation: Unconjugated
Poliovirus receptorrelated 2 (PVRL2) is also known as nectin2 and CD112 (formerly herpesvirus entry mediator B, HVEB), which is a human plasma membrane glycoprotein. PVRL2 is one of the plasma membrane components of adherens junctions. PVRL2 also serves as an entry for certain mutant strains of herpes simplex virus and pseudorabies virus, and it is involved in cell to cell spreading of these viruses. Variations in PVRL2 gene have been associated with differences in the severity of multiple sclerosis. Also, PVRL2 binds with low affinity to TIGIT. Furthermore, PVRL2 acts as a receptor for herpes simplex virus 1 (HHV1) mutant Rid1, herpes simplex virus 1 (HHV2) and pseudorabies virus (PRV). - Proteine/Peptide
Molekulargewicht: 62.4 kDa
Tag: C-mFc(mIgG2a)
NCBI: 92692
Puffer: Tris with Glycine, Arginine and NaCl, pH7.5
Reinheit: 95%
Formulierung: Powder
Target-Kategorie: Nectin-2
CD2-H5257-100ug
Immobilized Human DNAM-1, Fc Tag (Cat. No. DN1-H5257) at 5 µg/mL (100 µL/well) can bind Human Nectin-2, Mouse IgG2a Fc Tag (Cat. No. CD2-H5257) with a linear range of 2-78 ng/mL (QC tested).
Immobilized Biotinylated Human PVRIG, His,Avitag (Cat. No. PVG-H82E3) at 1 µg/mL (100 µL/well) on Streptavidin (Cat. No. STN-N5116) precoated (0.5 µg/well) plate, bind Human Nectin-2, Mouse IgG2a Fc Tag (Cat. No. CD2-H5257) with a linear range of 0.1-5 ng/mL (Routinely tested).
Human Nectin-2, Mouse IgG2a Fc Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.