Biotinylated Mouse Fc gamma RI / CD64 Protein, His,Avitag(TM) (MALS & SPR verified), Human

Produktübersicht

• Artikelname: Biotinylated Mouse Fc gamma RI / CD64 Protein, His,Avitag(TM) (MALS & SPR verified), Human
• Artikelnummer: ABS-CD4-M82E7-25UG
• Hersteller Artikelnummer: CD4-M82E7-25ug
• Alternativnummer: ABS-CD4-M82E7-25UG
• Hersteller: AcroBiosystems
• Wirt: Human
• Kategorie: Proteine/Peptide
• Spezies Reaktivität: Mouse
• Konjugation: Biotin

Produktbeschreibung

Receptors that recognize the Fc portion of IgG are divided into three groups designated Fc gamma RI, RII, and RIII, also known respectively as CD64, CD32, and CD16. Fc gamma RI binds IgG with high affinity and functions during early immune responses. Fc gamma RII and RIII are low affinity receptors that recognize IgG as aggregates surrounding multivalent antigens during late immune responses. High affinity immunoglobulin gamma Fc receptor I is also known as FCGR1A, FCG1, FCGR1, CD64 and IGFR1, is a type of integral membrane glycoprotein that binds monomeric IgGtype antibodies with high affinity, which belongs to the immunoglobulin superfamily or FCGR1 family. FCGR1A / CD64 contains 3 Iglike C2type (immunoglobulinlike) domains. CD64 is constitutively found on only macrophages and monocytes, but treatment of polymorphonuclear leukocytes with cytokines like IFNgamma and GCSF can induce CD64 expression on these cells. - Proteine/Peptide

Produkteigenschaften

• Molekulargewicht: 34.0 kDa
• Tag: C-10*His & C-Avi
• NCBI: 26151
• Puffer: PBS, pH7.4
• Reinheit: 90%
• Formulierung: Powder
• Target-Kategorie: Fc gamma RI / CD64

Bilder

Immobilized Biotinylated Mouse CD64, His,Avitag (Cat. No. CD4-M82E7) at 1 µg/mL (100 µL/well) on streptavidin (Cat. No. STN-N5116) precoated (0.5 µg/well) plate can bind Monoclonal Anti-Human CD3 Antibody, Mouse IgG2a (Clone: OKT3), premium grade (Cat. No. CDE-M120a) with a linear range of 0.06-4 ng/mL (Routinely tested).

Biotinylated Mouse CD64, His,Avitag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.

CD4-M82E7-25ug