Human CD5 Protein, Fc Tag, low endotoxin (MALS verified), Unconjugated

Artikelnummer: ABS-CD5-H5253-1MG
Artikelname: Human CD5 Protein, Fc Tag, low endotoxin (MALS verified), Unconjugated
Artikelnummer: ABS-CD5-H5253-1MG
Hersteller Artikelnummer: CD5-H5253-1mg
Alternativnummer: ABS-CD5-H5253-1MG
Hersteller: AcroBiosystems
Wirt: Human
Kategorie: Proteine/Peptide
Spezies Reaktivität: Human
Konjugation: Unconjugated
Tcell surface glycoprotein CD5 is also known as Lymphocyte antigen T1/Leu1 and LEU1,which is phosphorylated on tyrosine residues by LYN,so CD5 can create binding sites for PTPN6/SHP1.CD5 may act as a receptor in regulating Tcell proliferation. CD5 is expressed at various developmental and activation stages on human B cells.CD5 is a well established negative regulator of TCR and BCR signalling.CD5positive cells may also prevent the emergence of autoimmunity by provision of cytokines such as IL10. Development,selection and function of different B and Tcell subsets or their preferential survival may be directly or indirectly dependent on different glycan structures associated with CD5 or CD5like molecules. - Proteine/Peptide
Molekulargewicht: 65.1 kDa
Tag: C-Fc
NCBI: 06127
Puffer: PBS, pH7.4
Reinheit: 95%
Formulierung: Powder
Target-Kategorie: CD5
Immobilized Human CD5, Fc Tag (Cat. No. CD5-H5253) at 1 µg/mL (100 µL/well) can bind Monoclonal Anti-Human CD5 Antibody, Mouse IgG1 (2C8A7) with a linear range of 0.1-4 ng/mL (QC tested).
Human CD5, Fc Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.