Biotinylated Human CD206 / MMR Protein, His,Avitag(TM)

Produktübersicht

• Artikelname: Biotinylated Human CD206 / MMR Protein, His,Avitag(TM)
• Artikelnummer: ABS-CD6-H82E4-200UG
• Hersteller Artikelnummer: CD6-H82E4-200ug
• Alternativnummer: ABS-CD6-H82E4-200UG
• Hersteller: AcroBiosystems
• Wirt: Human
• Kategorie: Proteine/Peptide
• Spezies Reaktivität: Human
• Konjugation: Biotin

Produktbeschreibung

Mrc1 is a conserved checkpoint mediator protein that transduces the replication stress signal to the downstream effector kinase. Mrc1 and its vertebrate homologue Claspin serve as a mediator for replication stress checkpoint signaling, receiving the signal from Mec1/Rad3/ATR sensor kinase and transmitting it to the effector Rad53/Cds1/Chk1 kinase. The loss of mrc1 checkpoint activity results in the aberrant activation of late/dormant origins in the presence of hydroxyurea. Tumorassociated macrophages (TAMs) expressing the multiligand endocytic receptor mannose receptor (CD206/MRC1) contribute to tumor immunosuppression, angiogenesis, metastasis, and relapse. - Proteine/Peptide

Produkteigenschaften

• Molekulargewicht: 160.3 kDa
• Tag: C-10*His & C-Avi
• NCBI: 22897
• Puffer: PBS, pH7.4
• Reinheit: 90%
• Formulierung: Powder
• Target-Kategorie: CD206

Bilder

Immobilized Mannan at 20 µg/mL (100 µL/well) can bind Biotinylated Human CD206 Protein, His,Avitag (Cat. No. CD6-H82E4) with a linear range of 0.02-1.25 µg/mL (QC tested).

Biotinylated Human CD206 Protein, His,Avitag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.