Biotinylated Mouse CD206 / MMR Protein, His,Avitag(TM) (HPLC verified), Human
Artikelnummer:
ABS-CD6-M82E8-25UG
Hersteller Artikelnummer:
CD6-M82E8-25ug
Alternativnummer:
ABS-CD6-M82E8-25UG
Hersteller:
AcroBiosystems
Wirt:
Human
Kategorie:
Proteine/Peptide
Spezies Reaktivität:
Mouse
Konjugation:
Biotin
Mrc1 is a conserved checkpoint mediator protein that transduces the replication stress signal to the downstream effector kinase. Mrc1 and its vertebrate homologue Claspin serve as a mediator for replication stress checkpoint signaling, receiving the signal from Mec1/Rad3/ATR sensor kinase and transmitting it to the effector Rad53/Cds1/Chk1 kinase. The loss of mrc1 checkpoint activity results in the aberrant activation of late/dormant origins in the presence of hydroxyurea. Tumorassociated macrophages (TAMs) expressing the multiligand endocytic receptor mannose receptor (CD206/MRC1) contribute to tumor immunosuppression, angiogenesis, metastasis, and relapse. - Proteine/Peptide
Immobilized Mannan from Saccharomyces cerevisiae at 20 µg/mL (100 µL/well) can bind Biotinylated Mouse CD206 Protein, His,Avitag (Cat. No. CD6-M82E8) with a linear range of 0.078-0.625 µg/mL (QC tested).
Biotinylated Mouse CD206 Protein, His,Avitag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.
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