Biotinylated Mouse CD47 Protein, Fc,Avitag(TM) (MALS verified), Human
Artikelnummer:
ABS-CD7-M82F5-25UG
Hersteller Artikelnummer:
CD7-M82F5-25ug
Alternativnummer:
ABS-CD7-M82F5-25UG
Hersteller:
AcroBiosystems
Wirt:
Human
Kategorie:
Proteine/Peptide
Spezies Reaktivität:
Mouse
Konjugation:
Biotin
Leukocyte surface antigen CD47 is also known as Antigenic surface determinant protein OA3, Integrinassociated protein (IAP) and Protein MER6. CD47 contains 1 Iglike Vtype (immunoglobulinlike) domain. CD47 is very broadly distributed on normal adult tissues. CD47 has a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins and plays an important role in memory formation and synaptic plasticity in the hippocampus by similarity. CD47 is the receptor for SIRPA, binding to which prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells. CD47 Interaction with SIRPG mediates cellcell adhesion, enhances superantigendependent Tcellmediated proliferation and costimulates Tcell activation. - Proteine/Peptide
50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH7.5
Reinheit:
95%
Formulierung:
Powder
Target-Kategorie:
CD47
Immobilized Biotinylated Mouse CD47 Protein, Fc,Avitag (Cat. No. CD7-M82F5) at 1 µg/mL (100 µL/well) on streptavidin (Cat. No. STN-N5116) precoated (0.5 µg/well) plate can bind Mouse SIRP alpha Protein, Mouse IgG2a Fc Tag (Cat. No. SIA-M5252) with a linear range of 0.01-1.25 µg/mL (QC tested).
Biotinylated Mouse CD47 Protein, Fc,Avitag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.
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