Human CD98 Protein, Fc Tag, low Endotoxin (MALS verified), Unconjugated
Artikelnummer:
ABS-CD8-H5263-100UG
Hersteller Artikelnummer:
CD8-H5263-100ug
Alternativnummer:
ABS-CD8-H5263-100UG
Hersteller:
AcroBiosystems
Wirt:
Human
Kategorie:
Proteine/Peptide
Spezies Reaktivität:
Human
Konjugation:
Unconjugated
CD antigen CD98 is also known as 4F2 cellsurface antigen heavy chain (4F2hc), 4F2 heavy chain antigen, Solute carrier family 3 member 2 (SLC3A2), Lymphocyte activation antigen 4F2 large subunit, is a singlepass type I I membrane protein which belongs to the SLC3A transporter family.. SLC3A2 / CD98 is expressed ubiquitously in all tissues tested with highest levels detected in kidney, placenta and testis and weakest level in thymus. SLC3A2 / CD98 is required for the function of light chain aminoacid transporters and also involved in sodiumindependent, highaffinity transport of large neutral amino acids such as phenylalanine, tyrosine, leucine, arginine and tryptophan. CD98 involved in guiding and targeting of LAT1 and LAT2 to the plasma membrane. When associated with SLC7A5 or SLC7A8, CD98 involved in the cellular activity of small molecular weight nitrosothiols, via the stereoselective transport of Lnitrosocysteine (LCNSO) across the transmembrane. Together with ICAM1, regulates the transport activity LAT2 in polarized intestinal cells, by generating and delivering intracellular signals. - Proteine/Peptide
Immobilized Human CD98 Protein, Fc Tag (Cat. No. CD8-H5263) at 1 µg/mL (100 µL/well) can bind CD98 Recombinant Rabbit Monoclonal Antibody with a linear range of 0.05-2 ng/mL (QC tested).
Human CD98 Protein, Fc Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.
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