Mouse CD39 / ENTPD2 Protein, His Tag (active enzyme, MALS verified), Unconjugated, Human
Artikelnummer:
ABS-CD9-M52H3-500UG
Hersteller Artikelnummer:
CD9-M52H3-500ug
Alternativnummer:
ABS-CD9-M52H3-500UG
Hersteller:
AcroBiosystems
Wirt:
Human
Kategorie:
Proteine/Peptide
Spezies Reaktivität:
Mouse
Konjugation:
Unconjugated
CD39 is also known as Ectonucleoside triphosphate diphosphohydrolase 1, ENTPD1, NTPDase 1, EctoATPDase 1, in the nervous system, could hydrolyze ATP and other nucleotides to regulate purinergic neurotransmission. Could also be implicated in the prevention of platelet aggregation by hydrolyzing plateletactivating ADP to AMP. Hydrolyzes ATP and ADP equally well. NTPDase1 was originally described as CD39, a B lymphocyte cell surface marker, but it is also present on the surface of natural killer cells, T cells, and some endothelial cells.Regulatory T cells(Tregs) mediate immunosuppression through multiple, nonredundant, cellcontact dependent and independent mechanisms, a growing body of evidence suggests an important role for the CD39CD73adenosine pathway. CD39 ectonucleotidase is the ratelimiting enzyme of a cascade leading to the generation of suppressive adenosine that alters CD4 and CD8 T cell and natural killer cell antitumor activities. - Proteine/Peptide
Mouse CD39, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.
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