Human CD8 alpha&beta (CD8A&CD8B) Heterodimer Protein, His Tag&Tag Free (MALS verified), Unconjugated

Artikelnummer: ABS-CDA-H52W5-100UG
Artikelname: Human CD8 alpha&beta (CD8A&CD8B) Heterodimer Protein, His Tag&Tag Free (MALS verified), Unconjugated
Artikelnummer: ABS-CDA-H52W5-100UG
Hersteller Artikelnummer: CDA-H52W5-100ug
Alternativnummer: ABS-CDA-H52W5-100UG
Hersteller: AcroBiosystems
Wirt: Human
Kategorie: Proteine/Peptide
Spezies Reaktivität: Human
Konjugation: Unconjugated
Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. CD8A forms disulfidelinked heterodimers with CD8B at the cell surface. CD8A homodimer molecules also promote the survival and differentiation of activated lymphocytes into memory CD8 Tcells. Additionally, CD8B plays a critical role in thymic selection of CD8+ Tcells. A palmitoylation site in the cytoplasmic tail of CD8B chain contributes to partitioning of CD8 into the plasma membrane lipid rafts where signaling proteins are enriched. - Proteine/Peptide
Molekulargewicht: 19.5 kDa & 22.1 kDa
Tag: C-10*His | Native
NCBI: 01732
Puffer: PBS, pH7.4
Reinheit: 95%
Formulierung: Powder
Target-Kategorie: CD8 alpha & beta
CDA-H52W5-100ug
Immobilized Human CD8A&CD8B Heterodimer Protein, His Tag&Tag Free (Cat. No. CDA-H52W5) at 2 µg/mL (100 µL/well) can bind Anti-CD8 alpha Antibody, Mouse IgG2a (clone: OKT8) with a linear range of 0.06-4 ng/mL (QC tested).
Immobilized Anti-CD8 alpha Antibody,Mouse IgG2a (clone: OKT8) at 1 µg/mL (100 µL/well) can bind Human CD8A&CD8B Heterodimer Protein, His Tag&Tag Free (Cat. No. CDA-H52W5) with a linear range of 2-39 ng/mL (Routinely tested).
Human CD8A&CD8B Heterodimer Protein, His Tag&Tag Free on SDS-PAGE under reducing (R) and under non-reducing (NR) conditions. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.