Biotinylated Cynomolgus CD79B Protein, His,Avitag(TM), Human
Artikelnummer:
ABS-CDB-C82E5-25UG
Hersteller Artikelnummer:
CDB-C82E5-25ug
Alternativnummer:
ABS-CDB-C82E5-25UG
Hersteller:
AcroBiosystems
Wirt:
Human
Kategorie:
Proteine/Peptide
Spezies Reaktivität:
Monkey
Konjugation:
Biotin
Bcell antigen receptor complexassociated protein beta chain (CD79b) is also known as Bcellspecific glycoprotein B29, Igbeta,Immunoglobulinassociated B29 protein, B29 and IGB, which is a singlepass type I membrane protein containing one Iglike Vtype ( immunoglobulinlike ) domain and one ITAM domain.CD79b is required in cooperation with CD79A for initiation of the signal transduction cascade activated by the Bcell antigen receptor complex (BCR).CD79b can enhance phosphorylation of CD79A, possibly by recruiting kinases which phosphorylate CD79A or by recruiting proteins which bind to CD79A and protect it from dephosphorylation. Defects in CD79b are the cause of agammaglobulinemia type 6 (AGM6) that is a primary immunodeficiency characterized by profoundly low or absent serum antibodies and low or absent circulating B cells due to an early block of Bcell development. - Proteine/Peptide
Biotinylated Cynomolgus CD79B, His,Avitag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.
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