Human Fc gamma RIIIB / CD16b (NA2) Protein, Strep Tag (MALS & SPR verified), Unconjugated

Produktübersicht

• Artikelname: Human Fc gamma RIIIB / CD16b (NA2) Protein, Strep Tag (MALS & SPR verified), Unconjugated
• Artikelnummer: ABS-CDB-H5283-500UG
• Hersteller Artikelnummer: CDB-H5283-500ug
• Alternativnummer: ABS-CDB-H5283-500UG
• Hersteller: AcroBiosystems
• Wirt: Human
• Kategorie: Proteine/Peptide
• Spezies Reaktivität: Human
• Konjugation: Unconjugated

Produktbeschreibung

CD16 is a low affinity Fc receptor, and has been identified as Fc receptors FcgammaRIIIa (CD16a) and FcgammaRIIIb (CD16b). These receptors bind to the Fc portion of IgG antibodies. CD16 encoded by two different highly homologous genes in a cell typespecific manner.CD16 is found on the surface of natural killer cells, neutrophil polymorphonuclear leukocytes, monocytes and macrophages. CD16B is also kown as FCGR3B and FCG3B, is expressed specifically by polymorphonuclear leukocytes (neutrophils) and stimulated eosinophils. CD16B is the low affinity receptor for the Fc region of immunoglobulins gamma. FCGR3B binds complexed or aggregated IgG and also monomeric IgG. Contrary to IIIA, FCG3B is not capable to mediate antibodydependent cytotoxicity and phagocytosis. CD16B may serve as a trap for immune complexes in the peripheral circulation which does not activate neutrophils. - Proteine/Peptide

Produkteigenschaften

• Molekulargewicht: 24.2 kDa
• Tag: C-Twin-Strep
• NCBI: 75015
• Puffer: PBS, pH7.4
• Reinheit: 90%
• Formulierung: Powder
• Target-Kategorie: Fc gamma RIIIB / CD16b (NA2)

Bilder

Human CD16b (NA2) Protein, Strep Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.

CDB-H5283-500ug