Mouse Fc gamma RIIB / CD32b Protein, His Tag (SPR & BLI & MALS verified), Unconjugated, Human

Produktübersicht

• Artikelname: Mouse Fc gamma RIIB / CD32b Protein, His Tag (SPR & BLI & MALS verified), Unconjugated, Human
• Artikelnummer: ABS-CDB-M52H7-50UG
• Hersteller Artikelnummer: CDB-M52H7-50ug
• Alternativnummer: ABS-CDB-M52H7-50UG
• Hersteller: AcroBiosystems
• Wirt: Human
• Kategorie: Proteine/Peptide
• Spezies Reaktivität: Mouse
• Konjugation: Unconjugated

Produktbeschreibung

Receptors for the Fc region of IgG (Fc gamma R) are members of the Ig superfamily that function in the activation or inhibition of immune responses. Three classes of human Fc gamma Rs: RI (CD64), RII (CD32), and RIII (CD16), which generate multiple isoforms, are recognized. There are three genes for human Fcgamma RII /CD32 (A, B, and C) and one for mouse Fcgamma RII B (CD32B). CD32 is a low affinity receptor for IgG. Low affinity immunoglobulin gamma Fc region receptor IIb (FCGR2B) is also known as CD32b, FCG2, IGFR2. CD32B is expressed on B cells and myeloid dendritic cells. Ligation of CD32B on B cells downregulates antibody production and may, in some circumstances, promote apoptosis. Coligation of CD32B on dendritic cells inhibits maturation and blocks cell activation. CD32B may also be a target for monoclonal antibody therapy for malignancies. - Proteine/Peptide

Produkteigenschaften

• Molekulargewicht: 22.2 kDa
• Tag: C-10*His
• NCBI: 001070657
• Puffer: PBS, pH7.4
• Reinheit: 95%
• Formulierung: Powder
• Target-Kategorie: Fc gamma RIIB / CD32b

Bilder

Mouse CD32b, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.

CDB-M52H7-50ug