Human CD28H / IGPR-1 Protein, Fc Tag (MALS verified), Unconjugated
Artikelnummer:
ABS-CDH-H5251-1MG
Hersteller Artikelnummer:
CDH-H5251-1mg
Alternativnummer:
ABS-CDH-H5251-1MG
Hersteller:
AcroBiosystems
Wirt:
Human
Kategorie:
Proteine/Peptide
Spezies Reaktivität:
Human
Konjugation:
Unconjugated
CD28 homolog (CD28H), also called transmembrane and immunoglobulin domain containing 2 (TMIGD2) and IGPR1,is encoded by the TMIGD2 gene. CD28H is constitutively expressed on naive T and NK cells. After interaction of CD28 homolog with B7 homologue,the peripheral effector and memory T cells can be activated and proliferated by Aktdependent signalling cascade. Plays a role in cellcell interaction, cell migration, and angiogenesis. Through interaction with HHLA2, costimulates Tcells in the context of TCRmediated activation. Enhances Tcell proliferation and cytokine production via an AKTdependent signaling cascade. - Proteine/Peptide
Immobilized Human B7-H7, His Tag (Cat. No. B77-H52H6) at 5 µg/mL (100 µL/well) can bind Human CD28H, Fc Tag (Cat. No. CDH-H5251) with a linear range of 0.6-10 ng/mL (QC tested).
Human CD28H, Fc Tag on SDS-PAGE under reducing (R) and under non-reducing (NR) conditions. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.
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