Cynomolgus LILRB1 / CD85j / ILT2 Protein, His Tag, Unconjugated, Human

Produktübersicht

• Artikelname: Cynomolgus LILRB1 / CD85j / ILT2 Protein, His Tag, Unconjugated, Human
• Artikelnummer: ABS-CDJ-C52H3-100UG
• Hersteller Artikelnummer: CDJ-C52H3-100ug
• Alternativnummer: ABS-CDJ-C52H3-100UG
• Hersteller: AcroBiosystems
• Wirt: Human
• Kategorie: Proteine/Peptide
• Spezies Reaktivität: Monkey
• Konjugation: Unconjugated

Produktbeschreibung

CD85 antigenlike family member J (CD85J) is also known as Leukocyte immunoglobulinlike receptor subfamily B member 1 (LILRB1 or LIR1), Immunoglobulinlike transcript 2 (ILT2), Monocyte/macrophage immunoglobulinlike receptor 7 (MIR7), which belongs to leukocyte immunoglobulinlike receptor (LIR) family. CD85J / LILRB1 Contains 4 Iglike C2type (immunoglobulinlike) domains. CD85J / LIR1 is expressed predominantly on Bcells and monocytes. CD85J is receptor for class I MHC antigens and recognizes a broad spectrum of HLAA, HLAB, HLAC and HLAG alleles and is also receptor for H301/UL18, a human cytomegalovirus class I MHC homolog. Ligand binding results in inhibitory signals and downregulation of the immune response. CD85J / LILRB1 interaction with HLAB or HLAE leads to inhibition of the signal triggered by FCER1A and inhibits serotonin release. CD85J / LILRB1 inhibits FCGR1Amediated phosphorylation of cellular proteins and mobilization of intracellular calcium ions. - Proteine/Peptide

Produkteigenschaften

• Molekulargewicht: 49.0 kDa
• Tag: C-10*His
• NCBI: 045236898
• Puffer: PBS, pH7.4
• Reinheit: 95%
• Formulierung: Powder
• Target-Kategorie: LILRB1

Bilder

Cynomolgus LILRB1, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.