Cynomolgus LILRB4 / CD85k / ILT3 Protein, Fc Tag, Unconjugated, Human

Produktübersicht

• Artikelname: Cynomolgus LILRB4 / CD85k / ILT3 Protein, Fc Tag, Unconjugated, Human
• Artikelnummer: ABS-CDK-C5258-1MG
• Hersteller Artikelnummer: CDK-C5258-1mg
• Alternativnummer: ABS-CDK-C5258-1MG
• Hersteller: AcroBiosystems
• Wirt: Human
• Kategorie: Proteine/Peptide
• Spezies Reaktivität: Monkey
• Konjugation: Unconjugated

Produktbeschreibung

Leukocyte immunoglobulinlike receptor subfamily B member 4 (LILRB4) is also known as CD85 antigenlike family member K (CD85K), Immunoglobulinlike transcript 3 (ILT3), Leukocyte immunoglobulinlike receptor 5 (LIR5), Monocyte inhibitory receptor HM18, which belongs to the leukocyte immunoglobulinlike receptor (LIR) family. LILRB4 / CD85K contains 2 Iglike C2type (immunoglobulinlike) domains. CD85K is detected in monocytes, macrophages, dendritic cells, lung, natural killer cells and Bcells. LILRB4 / CD85K is receptor for class I MHC antigens. CD85K recognizes a broad spectrum of HLAA, HLAB, HLAC and HLAG alleles, involved in the downregulation of the immune response and the development of tolerance. LILRB4 interferes with TNFRSF5signaling and NFkappaB upregulation and inhibits receptormediated phosphorylation of cellular proteins and mobilization of intracellular calcium ions. - Proteine/Peptide

Produkteigenschaften

• Molekulargewicht: 52.7 kDa
• Tag: C-Fc
• NCBI: 015297198
• Puffer: Tris with Glycine, Arginine and NaCl, pH7.5
• Reinheit: 85%
• Formulierung: Powder
• Target-Kategorie: LILRB4

Bilder

Cynomolgus LILRB4, Fc Tag on SDS-PAGE under reducing (R) and under non-reducing (NR) conditions. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 85%.