Human CEACAM-6 / CD66c Protein, Fc Tag (MALS verified), Unconjugated
Artikelnummer:
ABS-CE6-H5254-100UG
Hersteller Artikelnummer:
CE6-H5254-100ug
Alternativnummer:
ABS-CE6-H5254-100UG
Hersteller:
AcroBiosystems
Wirt:
Human
Kategorie:
Proteine/Peptide
Spezies Reaktivität:
Human
Konjugation:
Unconjugated
Carcinoembryonic antigenrelated cell adhesion molecule 6 (nonspecific cross reacting antigen) (CEACAM6) is also known as CD66c (Cluster of Differentiation 66c), CEAL, NCA, and is one of seven human CEACAM family members within the immunoglobulin superfamily. In humans, CEACAMs include type I transmembrane proteins (CEACAM1, CEACAM3, and CEACAM4) and GPIlinked molecules (CEACAM5 through CEACAM8). There is no human CEACAM2. CEACAM 6 contains one Nterminal Vtype Iglike domain (N domain), followed by two C2type Iglike domains. It shows considerable glycosylation, including (sialyl) LewisX, which mediates binding to Eselectin, galectins and some bacterial fimbrae. CEACAM6 is expressed by granulocytes and their progenitors. It is also expressed by epithelia of various organs and is upregulated in pancreatic and colon adenocarcinomas, as well as hyperplastic polyps. Resistance to adhesionrelated apoptosis in tumor cells is conferred in the condition of CEACAM6 overexpression. - Proteine/Peptide
