Biotinylated Human Claudin-18.1 Protein, His,Flag Tag&Avitag(TM) (Detergent), Insect 20 ug

Produktübersicht

• Artikelname: Biotinylated Human Claudin-18.1 Protein, His,Flag Tag&Avitag(TM) (Detergent), Insect 20 ug
• Artikelnummer: ABS-CL1-H85D3-20UG
• Hersteller Artikelnummer: CL1-H85D3-20ug
• Alternativnummer: ABS-CL1-H85D3-20UG
• Hersteller: AcroBiosystems
• Wirt: Insect
• Kategorie: Proteine/Peptide
• Spezies Reaktivität: Human
• Konjugation: Biotin

Produktbeschreibung

This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. This gene is upregulated in patients with ulcerative colitis and highly overexpressed in infiltrating ductal adenocarcinomas. PKC/MAPK/AP1 (protein kinase C/mitogenactivated protein kinase/activator protein1) dependent pathway regulates the expression of this gene in gastric cells. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jun 2010] - Proteine/Peptide

Produkteigenschaften

• Molekulargewicht: 26.9 kDa
• Tag: N-10*His & C-Flag & C-Avi
• NCBI: 56856
• Puffer: 50 mM HEPES, 150 mM NaCl, DDM, pH7.5, CHS
• Reinheit: 80%
• Formulierung: Liquid
• Target-Kategorie: Claudin-18.1

Bilder

Immobilized Biotinylated Human Claudin-18.1 Protein, His,Flag Tag&Avitag (Cat. No. CL1-H85D3) at 1 µg/mL (100 µL/well) on streptavidin (Cat. No. STN-N5116) precoated (0.5 µg/well) plate can bind MonoclonalAnti-HumanClaudin18.1antibody,MouseIgG with a linear range of 0.5-16 ng/mL (QC tested).