Human Claudin-9 / CLDN9 Protein, His,Twin-Strep Tag (Detergent), Unconjugated, Insect

Produktübersicht

• Artikelname: Human Claudin-9 / CLDN9 Protein, His,Twin-Strep Tag (Detergent), Unconjugated, Insect
• Artikelnummer: ABS-CL9-H5586-20UG
• Hersteller Artikelnummer: CL9-H5586-20ug
• Alternativnummer: ABS-CL9-H5586-20UG
• Hersteller: AcroBiosystems
• Wirt: Insect
• Kategorie: Proteine/Peptide
• Spezies Reaktivität: Human
• Konjugation: Unconjugated

Produktbeschreibung

Claudin9 belongs to the claudin family. Claudins constitute integral membrane proteins responsible for solute and electrolyte permeability of the tight junction that serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets. Tight junctions also play a critical role in maintaining cell polarity and signal transductions. Claudin9 creates charge specific channels in the paracellular space, plays a major role in tight junctionspecific obliteration of the intercellular space, through calciumindependent celladhesion activity, is required to preserve sensory cells in the hearing organ because claudin9defective tight junctions fail to shield the basolateral side of hair cells from the K+rich endolymph. Its ion barrier function is essential in the cochlea, but appears to be dispensable in other organs. Is one of the entry cofactors for hepatitis C virus, it enables HCV entry into target cells just as efficiently as CLDN1. - Proteine/Peptide

Produkteigenschaften

• Molekulargewicht: 27.9 kDa
• Tag: N-10*His & C-Twin-Strep
• NCBI: 95484
• Puffer: 50 mM HEPES, 150 mM NaCl, DDM, CHS, pH7.5
• Reinheit: 90%
• Formulierung: Liquid
• Target-Kategorie: Claudin-9

Bilder

Immobilized HumanClaudin-9,His,Twin-StrepTag (Cat. No. CL9-H5586) at 5 µg/mL (100 µL/well) on a Nickel Coated plate can bind Anti-Claudin9Antibody with a linear range of 0.005-0.625 µg/mL (QC tested).

HumanClaudin-9,His,Twin-StrepTag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.

CL9-H5586-20ug