Human Clusterin / CLUS Protein, His Tag, Unconjugated

Produktübersicht

• Artikelname: Human Clusterin / CLUS Protein, His Tag, Unconjugated
• Artikelnummer: ABS-CLU-H5227-100UG
• Hersteller Artikelnummer: CLU-H5227-100ug
• Alternativnummer: ABS-CLU-H5227-100UG
• Hersteller: AcroBiosystems
• Wirt: Human
• Kategorie: Proteine/Peptide
• Spezies Reaktivität: Human
• Konjugation: Unconjugated

Produktbeschreibung

Clusterin (CLU) is also known as dimeric acidic glycoprotein (DAG protein), testosterone repressed prostate message2 (TRPM2), sulfated glycoprotein2 (SGP2) and complement lysis inhibitor (CLI), is a secreted multifunctional glycoprotein protein which belongs to the clusterin family. Intracellular cleavages of the precursor of clusterin remove the signal peptide and generate comparably sized alpha and beta chains which are secreted as an 80 kDa Nglycosylated disulfidelinked heterodimer. DAG protein is predominantly expressed in adult testis, ovary, adrenal gland, liver, heart, and brain and in many epithelial tissues during embryonic development. Clusterin involve in several basic biological events such as cell death, tumor progression, and neurodegenerative disorders. Upregulation of clusterin mRNA and protein levels detected in diverse disease states and in in vitro systems have led to suggestions that it functions in membrane lipid recycling, in apoptotic cell death, and as a stressinduced secreted chaperone protein, amongst others. - Proteine/Peptide

Produkteigenschaften

• Molekulargewicht: 50.9 kDa
• Tag: C-6*His
• NCBI: 001822
• Puffer: PBS, pH7.4
• Reinheit: 95%
• Formulierung: Powder
• Target-Kategorie: Clusterin

Bilder

Human Clusterin, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.

CLU-H5227-100ug