HCMV Glycoprotein B (gB) Protein, Fc Tag, Unconjugated, Human
Artikelnummer:
ABS-CMB-V5255-50UG
Hersteller Artikelnummer:
CMB-V5255-50ug
Alternativnummer:
ABS-CMB-V5255-50UG
Hersteller:
AcroBiosystems
Wirt:
Human
Kategorie:
Proteine/Peptide
Spezies Reaktivität:
HCMV
Konjugation:
Unconjugated
Human cytomegalovirus is a species of the Cytomegalovirus genus of viruses, which in turn is a member of the viral family known as Herpesviridae or herpesviruses. It is typically abbreviated as HCMV or, commonly but more ambiguously, as CMV. CMV Virus Envelope Glycoportein B (CMVGB) can be cleaved into glycoprotein GP55. Envelope glycoprotein that plays a role in host cell entry, cell tocell virus transmission, and fusion of infected cells. CMVGB may be involved in the initial attachment via binding to heparan sulfate together with the gM/gN complex that binds heparin with higher affinity. Furthermore, CMVGB can interact with host integrin ITGB1, PDGFRA and EGFR that likely serve as postattachment entry receptors. Also, CMVGB participates in the fusion of viral and cellular membranes leading to virus entry into the host cell. Membrane fusion is mediated by the fusion machinery composed at least of gB and the heterodimer gH/gL. - Proteine/Peptide
HCMV Glycoprotein B (gB) Protein, Fc Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.
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