Human Contactin-2 / Tag1 / CNTN2 Protein, His Tag, Unconjugated
Artikelnummer:
ABS-CN2-H5226-1MG
Hersteller Artikelnummer:
CN2-H5226-1mg
Alternativnummer:
ABS-CN2-H5226-1MG
Hersteller:
AcroBiosystems
Wirt:
Human
Kategorie:
Proteine/Peptide
Spezies Reaktivität:
Human
Konjugation:
Unconjugated
Contactin2 is also known as CNTN2, TAX1 (transientlyexpressed axonal glycoprotein), TAG1 (transient axonal glycoprotein), and axonin1, and is a member of the immunoglobulin superfamily. CNTN2 consists of six Iglike domains and four fibronectin type III domains, and is anchored to the membrane by glycosylphosphatidylinositol (GPI), whereas the soluble form can be released by a GPIspecific phospholipase. As a neural cell adhesion molecule expressed by a subset of neuronal populations in the developing CNS and PNS, CNTN2 mediates cellcell interactions either via homophilic, or heterophilic contacts with various adhesion molecules including NgCAM, NrCAM, NCAM and neurocan. It is a glycosylphosphatidylinositol (GPI)anchored neuronal membrane protein that functions as a cell adhesion molecule. It may play a role in the formation of axon connections in the developing nervous system. It may also be involved in glial tumorigenesis and may provide a potential target for therapeutic intervention. - Proteine/Peptide
