Human Cathepsin B / CTSB Protein, His Tag (MALS verified), Unconjugated

Produktübersicht

• Artikelname: Human Cathepsin B / CTSB Protein, His Tag (MALS verified), Unconjugated
• Artikelnummer: ABS-CTB-H5222-50UG
• Hersteller Artikelnummer: CTB-H5222-50ug
• Alternativnummer: ABS-CTB-H5222-50UG
• Hersteller: AcroBiosystems
• Wirt: Human
• Kategorie: Proteine/Peptide
• Spezies Reaktivität: Human
• Konjugation: Unconjugated

Produktbeschreibung

Cathepsin B (CTSB) is also known as APP secretase (APPS) and CPSB, is an enzymatic protein belonging to the peptidase C1 family. Cathepsin B / CTSB is synthesized as a preproenzyme. Following removal of the signal peptide, the inactive proenzyme undergoes further modifications including removal of the pro region to result in the active enzyme. The catalytic activity of Cathepsin B / APPS contains: Hydrolysis of proteins with broad specificity for peptide bonds, Preferentially cleaves ArgArg|Xaa bonds in small molecule substrates (thus differing from cathepsin L), In addition to being an endopeptidase, shows peptidyldipeptidase activity, liberating Cterminal dipeptides. As a thiol protease, cathepsin B / CPSB is believed to participate in intracellular degradation and turnover of proteins and has also been implicated in tumor invasion and metastasis. Overexpression of cathepsin B has been associated with esophageal adenocarcinoma and other tumors. - Proteine/Peptide

Produkteigenschaften

• Molekulargewicht: 36.7 kDa & 29.5 kDa
• Tag: C-6*His
• NCBI: 07858
• Puffer: 50 mM Tris, 150 mM NaCl, pH8.0
• Reinheit: 95%
• Formulierung: Powder
• Target-Kategorie: Cathepsin B

Bilder

Human Cathepsin B, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.