Human SMAC / Diablo Protein, His Tag, Unconjugated, E. coli

Produktübersicht

• Artikelname: Human SMAC / Diablo Protein, His Tag, Unconjugated, E. coli
• Artikelnummer: ABS-DIO-H5129-200UG
• Hersteller Artikelnummer: DIO-H5129-200ug
• Alternativnummer: ABS-DIO-H5129-200UG
• Hersteller: AcroBiosystems
• Wirt: E. coli
• Kategorie: Proteine/Peptide
• Spezies Reaktivität: Human
• Konjugation: Unconjugated

Produktbeschreibung

Diablo homolog, mitochondrial (DIABLO) is also known as direct IAPbinding protein with low pI and second mitochondriaderived activator of caspase (SMAC), which can interact with BIRC2/cIAP1, BIRC3/cIAP2, XIAP/BIRC4, BIRC6/bruce and BIRC7/livin. Acting by opposing the inhibitory activity of inhibitor of apoptosis proteins (IAP),DIABLO can also promote apoptosis by activating caspases in the cytochrome c/Apaf1/caspase9 pathway. Also, DIABLO inhibits the activity of BIRC6/bruce by inhibiting its binding to caspases. Furthermore, DIABLO is defective in the capacity to downregulate the XIAP/BIRC4 abundance. - Proteine/Peptide

Produkteigenschaften

• Molekulargewicht: 21.7 kDa
• Tag: C-6*His
• NCBI: 063940
• Puffer: 20 mM HEPES, 150 mM NaCl, pH7.5
• Reinheit: 95%
• Formulierung: Powder
• Target-Kategorie: SMAC

Bilder

Human SMAC, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.