Human E-Cadherin / Cadherin-1 (155-709) Protein, Fc Tag (MALS verified), Unconjugated

Produktübersicht

• Artikelname: Human E-Cadherin / Cadherin-1 (155-709) Protein, Fc Tag (MALS verified), Unconjugated
• Artikelnummer: ABS-ECD-H5256-1MG
• Hersteller Artikelnummer: ECD-H5256-1mg
• Alternativnummer: ABS-ECD-H5256-1MG
• Hersteller: AcroBiosystems
• Wirt: Human
• Kategorie: Proteine/Peptide
• Spezies Reaktivität: Human
• Konjugation: Unconjugated

Produktbeschreibung

Cadherins are calciumdependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells, cadherins may thus contribute to the sorting of heterogeneous cell types. Cadherin1 (CDH1) is also known as epithelial cadherin (Ecadherin), CD_antigen (CD324), Uvomorulin (UVO) ECAD and CDHE, CDH1 / CD324 contains 5 cadherin domains. CDH1 / CD324 / ECAD is expressed in nonneural epithelial tissues. CDH1 / ECAD is involved in mechanisms regulating cellcell adhesions, mobility and proliferation of epithelial cells and has a potent invasive suppressor role. It is a ligand for integrin alphaE/beta7. ECad promotes nonamyloidogenic degradation of Abeta precursors and has a strong inhibitory effect on APP C99 and C83 production. Defects in CDH1 / CD324 / ECAD are the cause of hereditary diffuse gastric cancer (HDGC). - Proteine/Peptide

Produkteigenschaften

• Molekulargewicht: 87.0 kDa
• Tag: C-Fc
• NCBI: 12830
• Puffer: 20 mM Tris, 150 mM NaCl, pH8.0
• Reinheit: 90%
• Formulierung: Powder
• Target-Kategorie: E-Cadherin

Bilder

Immobilized Mouse KLRG1, His Tag (Cat. No. KL1-M5249) at 5 µg/mL (100 µL/well) can bind Human E-Cadherin (155-709) Protein, Fc Tag (Cat. No. ECD-H5256) with a linear range of 0.02-1.25 µg/mL (QC tested).

Human E-Cadherin (155-709) Protein, Fc Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.