Human EDNRB Full Length Protein (VLP), Unconjugated 20 ug

Produktübersicht

• Artikelname: Human EDNRB Full Length Protein (VLP), Unconjugated 20 ug
• Artikelnummer: ABS-EDB-H52P7-20UG
• Hersteller Artikelnummer: EDB-H52P7-20ug
• Alternativnummer: ABS-EDB-H52P7-20UG
• Hersteller: AcroBiosystems
• Wirt: Human
• Kategorie: Proteine/Peptide
• Spezies Reaktivität: Human
• Konjugation: Unconjugated

Produktbeschreibung

Endothelin Receptor B (EDNRB) is a type of G proteincoupled Receptor with the Nterminus located outside the cell. Its widespread in the human body. EDNRB binds to ET and transmits information into the cell through the intracellular Ca2+ phospholipiddependent protein kinase second messenger system, which promotes the rapid release of calcium in the endoplasmic reticulum and sarcoplasmic reticulum, resulting in the rapid increase of intracellular calcium concentration. Endothelin exerts its biological effects through its receptor (ETR). Endothelin and ETR constitute the endothelin axis. Endothelin axis has protumor effects in various tumors including malignant melanoma (MM), including promoting tumor growth, antiapoptosis, promoting angiogenesis and promoting tumor metastasis. - Proteine/Peptide

Produkteigenschaften

• NCBI: 24530
• Puffer: PBS, Arginine, pH7.4
• Formulierung: Liquid
• Target-Kategorie: EDNRB

Bilder

Immobilized Human EDNRB Full Length Protein-VLP (Cat. No. EDB-H52P7) at 5 µg/mL (100 µL/well) can bind Anti-EDNRB Antibody, Human IgG1 with a linear range of 0.1-2 ng/mL (QC tested).