Human Endoglin / CD105 Protein, His Tag, Unconjugated
Artikelnummer:
ABS-ENN-H52H9-50UG
Hersteller Artikelnummer:
ENN-H52H9-50ug
Alternativnummer:
ABS-ENN-H52H9-50UG
Hersteller:
AcroBiosystems
Wirt:
Human
Kategorie:
Proteine/Peptide
Spezies Reaktivität:
Human
Konjugation:
Unconjugated
Endoglin (ENG), endothelial glycoprotein, also known as CD105, is a coreceptor of the transforming growth factorbeta (TGFbeta) family signaling complex, which is highly expressed on endothelial cells and plays a key role in angiogenesis. It regulates the responses associated with binding to transforming growth factor beta1 egg (ActivinA), bone morphogenetic protein 2 (BMP2), and bone morphogenetic protein 7 (BMP7). Endoglin may be involved in autosomal dominant disease, such as hereditary hemorrhagic telangiectasia 1 (HHT1). Circulating soluble ENG is also elevated in pulmonary arterial hypertension(PAH) and is proposed to be a biomarker for the prognosis of group I PAH patients. - Proteine/Peptide
Human Endoglin Protein, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.
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