Human Endoglin / CD105 Protein, His Tag, Unconjugated

Artikelnummer: ABS-ENN-H52H9-50UG
Artikelname: Human Endoglin / CD105 Protein, His Tag, Unconjugated
Artikelnummer: ABS-ENN-H52H9-50UG
Hersteller Artikelnummer: ENN-H52H9-50ug
Alternativnummer: ABS-ENN-H52H9-50UG
Hersteller: AcroBiosystems
Wirt: Human
Kategorie: Proteine/Peptide
Spezies Reaktivität: Human
Konjugation: Unconjugated
Endoglin (ENG), endothelial glycoprotein, also known as CD105, is a coreceptor of the transforming growth factorbeta (TGFbeta) family signaling complex, which is highly expressed on endothelial cells and plays a key role in angiogenesis. It regulates the responses associated with binding to transforming growth factor beta1 egg (ActivinA), bone morphogenetic protein 2 (BMP2), and bone morphogenetic protein 7 (BMP7). Endoglin may be involved in autosomal dominant disease, such as hereditary hemorrhagic telangiectasia 1 (HHT1). Circulating soluble ENG is also elevated in pulmonary arterial hypertension(PAH) and is proposed to be a biomarker for the prognosis of group I PAH patients. - Proteine/Peptide
Molekulargewicht: 62.6 kDa
Tag: C-10*His
NCBI: 17813
Puffer: PBS, pH7.4
Reinheit: 95%
Formulierung: Powder
Target-Kategorie: Endoglin
Human Endoglin Protein, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.