Human cytomegalovirus (strain Merlin) (HHV-5) Envelope protein H&L&UL128&UL130&UL131, Twin-Strep Tag&His Tag (MALS verified), Unconjugated

Produktübersicht

• Artikelname: Human cytomegalovirus (strain Merlin) (HHV-5) Envelope protein H&L&UL128&UL130&UL131, Twin-Strep Tag&His Tag (MALS verified), Unconjugated
• Artikelnummer: ABS-ENN-V5283-500UG
• Hersteller Artikelnummer: ENN-V5283-500ug
• Alternativnummer: ABS-ENN-V5283-500UG
• Hersteller: AcroBiosystems
• Wirt: Human
• Kategorie: Proteine/Peptide
• Spezies Reaktivität: Virus
• Konjugation: Unconjugated

Produktbeschreibung

Human cytomegalovirus (HCMV), a prototypical betaherpes virus, is a major cause of morbidity and mortality in immunocompromised transplant recipients and congenitally infected fetuses.Different HCMV glycoprotein complexes are capable of meditating entry through interaction with cellspecific receptors on a panel of host cells. The pentamer (gH/gL/UL128/UL130/UL131A) mediates HCMV entry into epithelial, endothelial, and myeloid cells by its binding to neuropilin 2 (Nrp2). The trimer (gH/gL/gO) can mediate infection of all cell types by binding to plateletderived growth factoralpha (PDGFRalpha). Both pentamer and trimer need to interact with the glycoprotein B (gB), the fusogenic protein, to trigger the virus and host cell membrane fusion. - Proteine/Peptide

Produkteigenschaften

• Molekulargewicht: 110.8 kDa (H&L) & 16.7 kDa (UL128) & 23.7 kDa (UL130) & 13.0 kDa (UL131)
• Tag: N-Twin Strep | Native | C-10*His | Native
• NCBI: 6
• Puffer: PBS, pH7.4
• Reinheit: 90%
• Formulierung: Powder
• Target-Kategorie: Envelope protein H&L&UL128&UL130&UL131

Bilder

Immobilized Human Neuropilin-2, His Tag (Cat. No. NR2-H52H3) at 5 µg/mL (100 µL/well) can bind Human cytomegalovirus Envelope protein H&L&UL128&UL130&UL131, Twin-Strep Tag&His Tag (Cat. No. ENN-V5283) with a linear range of 0.004-0.125 µg/mL (QC tested).

Human cytomegalovirus Envelope protein H&L&UL128&UL130&UL131, Twin-Strep Tag&His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.

ENN-V5283-500ug