Human Erythropoietin R / EPO R Protein, His Tag (MALS & SPR verified), Unconjugated

Artikelnummer: ABS-EPR-H52H4-100UG
Artikelname: Human Erythropoietin R / EPO R Protein, His Tag (MALS & SPR verified), Unconjugated
Artikelnummer: ABS-EPR-H52H4-100UG
Hersteller Artikelnummer: EPR-H52H4-100ug
Alternativnummer: ABS-EPR-H52H4-100UG
Hersteller: AcroBiosystems
Wirt: Human
Kategorie: Proteine/Peptide
Spezies Reaktivität: Human
Konjugation: Unconjugated
This gene encodes the erythropoietin receptor which is a member of the cytokine receptor family. Upon erythropoietin binding, this receptor activates Jak2 tyrosine kinase which activates different intracellular pathways including: Ras/MAP kinase, phosphatidylinositol 3kinase and STAT transcription factors. The stimulated erythropoietin receptor appears to have a role in erythroid cell survival. Defects in the erythropoietin receptor may produce erythroleukemia and familial erythrocytosis. Dysregulation of this gene may affect the growth of certain tumors. Alternate splicing results in multiple transcript variants. - Proteine/Peptide
Molekulargewicht: 26.7 kDa
Tag: C-10*His
NCBI: 19235
Puffer: PBS, pH7.4
Reinheit: 90%
Formulierung: Powder
Target-Kategorie: Erythropoietin R
Human Erythropoietin R Protein, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.
EPR-H52H4-100ug
Immobilized Human Erythropoietin R Protein, His Tag (Cat. No. EPR-H52H4) at 5 µg/mL (100 µL/well) can bind Human Erythropoietin Protein, Fc Tag (Cat. No. EPO-H5253) with a linear range of 0.2-2 ng/mL (Routinely tested).