Monoclonal Anti-Eribulin Antibody, Rabbit IgG (1M2B11), Unconjugated, Human

Produktübersicht

• Artikelname: Monoclonal Anti-Eribulin Antibody, Rabbit IgG (1M2B11), Unconjugated, Human
• Artikelnummer: ABS-ERN-MY2063B-1MG
• Hersteller Artikelnummer: ERN-MY2063b-1mg
• Alternativnummer: ABS-ERN-MY2063B-1MG
• Hersteller: AcroBiosystems
• Wirt: Human
• Kategorie: Antikörper
• Spezies Reaktivität: Rabbit
• Konjugation: Unconjugated

Produktbeschreibung

Eribulin is a synthetic analogue of the macrocyclic polyether halichondrin B, which was originally isolated from the Asian sea sponge Halichondria okadai. Eribulin binds specifically to the betatubulin subunit on the (+) end of the microtubule and potently inhibits elongation of the formed microtubule, while having little or no effect on microtubule depolymerization. Eribulins potent antimitotic activity and nonmitotic effects on tumor biology make it an interesting candidate for investigation as a MTA payload for ADCs. - Antikörper

Produkteigenschaften

• Tag: Rabbit IgG | Rabbit Kappa
• Puffer: PBS, pH7.4
• Formulierung: Powder
• Target-Kategorie: Eribulin

Bilder

Immobilized Monoclonal Anti-Eribulin Antibody, Rabbit IgG (1M2B11) (Cat. No. ERN-MY2063b) at 1 µg/mL, add FarletuzumabEcteribulin in the 100% Human Serum and then add Biotinylated Human FOLR1, Fc,Avitag (Cat. No. FO1-H82F9) at 0.5 µg/mL. Detection was performed using HRP-conjugated Streptavidin (Acro, Cat. No. STN-NH913) (QC tested).

Immobilized Farletuzumab Ecteribulin at 1 µg/mL (100 µL/well) can bind Monoclonal Anti-Eribulin Antibody, Rabbit IgG (1M2B11) (Cat. No. ERN-MY2063b) with a linear range of 0.06-2 ng/mL (Routinely tested).