CD45 is a receptor protein tyrosine phosphatase, also known as Ly5 or leukocyte common antigen. CD45 mainly involves in the initiation of T cell receptor signaling by controlling the activation of the Src family proteintyrosine kinases Lck and Fyn. CD45 deficiency causes in T and Blymphocyte dysfunction in the form of severe combined immune deficiency. It also takes a significant role in autoimmune diseases and cancer as well as in infectious diseases including fungal infections. - Antikörper
Tag:
Mouse IgG2b | Mouse kappa
Puffer:
PBS, pH7.4, 0.03% Proclin300, 0.2% BSA
Formulierung:
Liquid
Target-Kategorie:
CD45RA
Anwendungsbeschreibung:
Flow Cytometry (Evaluation of the expression of CD45RA on Human cells).
FABm040-01-200tests
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