Biotinylated Mouse Fc gamma RIV / CD16-2 Protein, His,Avitag(TM) (HPLC & BLI verified), Human
Artikelnummer:
ABS-FC4-M82E8-25UG
Hersteller Artikelnummer:
FC4-M82E8-25ug
Alternativnummer:
ABS-FC4-M82E8-25UG
Hersteller:
AcroBiosystems
Wirt:
Human
Kategorie:
Proteine/Peptide
Spezies Reaktivität:
Mouse
Konjugation:
Biotin
FcgR4(Low affinity immunoglobulin gamma Fc region receptor IV) is also known as CD162, FcgammaRIV, receptor for the Fc region of immunoglobulin gamma . Also acts as a receptor for the Fc region of immunoglobulin epsilon . Binds with intermediate affinity to both IgG2a and IgG2b . Does not display binding to IgG1 or IgG3. Plays a role in promoting bone resorption by enhancing osteoclast differentiation following binding to IgG2a. Binds with low affinity to both the a and b allotypes of IgE. Has also been shown to bind to IgE allotype a only but not to allotype b. Binding to IgE promotes macrophagemediated phagocytosis, antigen presentation to T cells, production of proinflammatory cytokines and the late phase of cutaneous allergic reactions - Proteine/Peptide
Immobilized FMC63 at 5 µg/mL (100 µL/well) can bind Biotinylated Mouse CD16-2 Protein, His,Avitag (Cat. No. FC4-M82E8) with a linear range of 0.3-20 ng/mL (Routinely tested).
Biotinylated Mouse CD16-2 Protein, His,Avitag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.
FC4-M82E8-25ug
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