Human Fc epsilon RI alpha Protein, His Tag (MALS verified), Unconjugated
Artikelnummer:
ABS-FCA-H5228-100UG
Hersteller Artikelnummer:
FCA-H5228-100ug
Alternativnummer:
ABS-FCA-H5228-100UG
Hersteller:
AcroBiosystems
Wirt:
Human
Kategorie:
Proteine/Peptide
Spezies Reaktivität:
Human
Konjugation:
Unconjugated
High affinity immunoglobulin epsilon receptor subunit alpha (FCER1A) is also known as Fcepsilon RIalpha (FcERI), IgE Fc receptor subunit alpha, FCE1A. FCER1A contains two Iglike (immunoglobulinlike) domains. FCER1A binds to the Fc region of immunoglobulins epsilon and is a high affinity receptor. FCER1A is responsible for initiating the allergic response, which binding of allergen to receptorbound IgE leads to cell activation and the release of mediators (such as histamine) responsible for the manifestations of allergy. The same receptor also induces the secretion of important lymphokines. FCER1A plays a central role in allergic disease, coupling allergen and mast cell to initiate the inflammatory and immediate hypersensitivity responses that are characteristic of disorders such as hay fever and asthma. - Proteine/Peptide
Immobilized Immunoglobulin E, Human Plasma at 5 µg/mL (100 µL/well) can bind Human Fc epsilon RI alpha, His Tag (Cat. No. FCA-H5228) with a linear range of 0.4-3 ng/mL (QC tested).
Human Fc epsilon RI alpha, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.
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