Human Fc epsilon RI alpha Protein, Fc Tag (MALS & BLI verified), Unconjugated

Artikelnummer: ABS-FCA-H5259-1MG
Artikelname: Human Fc epsilon RI alpha Protein, Fc Tag (MALS & BLI verified), Unconjugated
Artikelnummer: ABS-FCA-H5259-1MG
Hersteller Artikelnummer: FCA-H5259-1mg
Alternativnummer: ABS-FCA-H5259-1MG
Hersteller: AcroBiosystems
Wirt: Human
Kategorie: Proteine/Peptide
Spezies Reaktivität: Human
Konjugation: Unconjugated
High affinity immunoglobulin epsilon receptor subunit alpha (FCER1A) is also known as Fcepsilon RIalpha (FcERI), IgE Fc receptor subunit alpha, FCE1A. FCER1A contains two Iglike (immunoglobulinlike) domains. FCER1A binds to the Fc region of immunoglobulins epsilon and is a high affinity receptor. FCER1A is responsible for initiating the allergic response, which binding of allergen to receptorbound IgE leads to cell activation and the release of mediators (such as histamine) responsible for the manifestations of allergy. The same receptor also induces the secretion of important lymphokines. FCER1A plays a central role in allergic disease, coupling allergen and mast cell to initiate the inflammatory and immediate hypersensitivity responses that are characteristic of disorders such as hay fever and asthma. - Proteine/Peptide
Molekulargewicht: 47.3 kDa
Tag: C-Fc
NCBI: 12319
Puffer: Tris with Glycine, Arginine and NaCl, pH7.5
Reinheit: 95%
Formulierung: Powder
Target-Kategorie: Fc epsilon RI alpha
Immobilized Human Fc epsilon RI alpha, Fc Tag (Cat. No. FCA-H5259) at 5 µg/mL (100 µL/well) can bind Human IgE Fc, His Tag (Cat. No. IGE-H52H9) with a linear range of 0.6-20 ng/mL (Routinely tested).
Human Fc epsilon RI alpha, Fc Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.
FCA-H5259-1mg