Human Fetuin A / FETUA Protein, His Tag, Unconjugated
Artikelnummer:
ABS-FEA-H5221-1MG
Hersteller Artikelnummer:
FEA-H5221-1mg
Alternativnummer:
ABS-FEA-H5221-1MG
Hersteller:
AcroBiosystems
Wirt:
Human
Kategorie:
Proteine/Peptide
Spezies Reaktivität:
Human
Konjugation:
Unconjugated
Alpha2HSglycoprotein (AHSG) is also known as Alpha2Zglobulin, Baalpha2glycoprotein, FetuinA (FETUA), is a glycoprotein that is composed of two subunits, the A and B chains, belongs to the cystatin family of proteases inhibitors and the fetuin class of plasma binding proteins. AHSG / Fetuin A is highly expressed in embryonic cells and adult hepatocytes, and is expressed to a lesser extent in monocytes/macrophages. Fetuins are carrier proteins like albumin. FetuinA / AHSG forms soluble complexes with calcium and phosphate and thus is a carrier of otherwise insoluble calcium phosphate. Thus AHSG / Fetuin A is a potent inhibitor of pathological calcification. Fetuin A / FETUA promotes phagocytosis of apoptotic cells and plays a role in bone development, calcium homeostasis and insulin sensitivity. Mice deficient in FetuinA show systemic calcification of soft tissues. - Proteine/Peptide
Human Fetuin A, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 98%.
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