Human Coagulation factor XI / FXI Protein, His Tag (active enzyme), Unconjugated
Artikelnummer:
ABS-FXI-H52H5-50UG
Hersteller Artikelnummer:
FXI-H52H5-50ug
Alternativnummer:
ABS-FXI-H52H5-50UG
Hersteller:
AcroBiosystems
Wirt:
Human
Kategorie:
Proteine/Peptide
Spezies Reaktivität:
Human
Konjugation:
Unconjugated
Coagulation factor XI is also known as F11, PTA and FXI. Factor XI triggers the middle phase of the intrinsic pathway of blood coagulation by activating factor IX. Factor XI is synthesized in the liver and circulates in the plasma as a disulfide bondlinked dimer complexed with high molecular weight kininogen. Selective cleavage of Arg|Ala and Arg|Val bonds in factor IX to form factor IXa. Factor XI is converted into XIa via either the contact phase of blood coagulation or thrombinmediated activation on the platelet surface. The resulting XIa converts factor IX into IXa, which subsequently activates factor X into Xa. - Proteine/Peptide
Immobilized Human Coagulation factor XI, His Tag (Cat. No. FXI-H52H5) at 1 µg/mL (100 µL/well) can bind Abelacimab with a linear range of 0.2-8 ng/mL (QC tested).
Immobilized Abelacimab at 1 µg/mL (100 µL/well) can bind Human Coagulation factor XI, His Tag (Cat. No. FXI-H52H5) with a linear range of 2-31 ng/mL (Routinely tested).
Human Coagulation factor XI, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.
FXI-H52H5-50ug
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