Human GCGR Protein, Flag,His Tag (Detergent), Unconjugated

Artikelnummer: ABS-GCR-H52D3-100UG
Artikelname: Human GCGR Protein, Flag,His Tag (Detergent), Unconjugated
Artikelnummer: ABS-GCR-H52D3-100UG
Hersteller Artikelnummer: GCR-H52D3-100ug
Alternativnummer: ABS-GCR-H52D3-100UG
Hersteller: AcroBiosystems
Wirt: Human
Kategorie: Proteine/Peptide
Spezies Reaktivität: Human
Konjugation: Unconjugated
The protein encoded by this gene is a glucagon receptor that is important in controlling blood glucose levels. Defects in this gene are a cause of type 2 diabetes mellitus (T2DM) . The ever increasing prevalence of type 2 diabetes mellitus in the developed and developing nations calls for the introduction of new and more effective treatments. Glucagon receptor (GCGR) antagonists are highly validated in preclinical models of T2DM and thus have the potential to be developed as a new therapy. - Proteine/Peptide
Molekulargewicht: 83.2 kDa
Tag: N-Flag & C-10*His
NCBI: 47871
Puffer: 50 mM HEPES, 150 mM NaCl, DDM, CHS, pH7.5
Formulierung: Liquid
Target-Kategorie: GCGR
Immobilized Human GCGR Protein, Flag,His Tag (Cat. No. GCR-H52D3) at 5 µg/mL (100 µL/well) on a Nickel Coated plate can bind Monoclonal Anti-Human GCGR antibody, Human IgG2 (Volagidemab) (Cat. No. GCR-H52D3) with a linear range of 0.1-3 ng/mL (QC tested).
Immobilized Human GCGR Protein, Flag,His Tag (Cat. No. GCR-H52D3) at 5 µg/mL (100 µL/well) on a Nickel Coated plate can bind Monoclonal Anti-Human GCGR antibody, Human IgG4 (Crotedumab) with a linear range of 0.1-3 ng/mL (Routinely tested).