Human Growth Hormone R (GHR) Protein, His Tag (MALS verified), Unconjugated

Produktübersicht

• Artikelname: Human Growth Hormone R (GHR) Protein, His Tag (MALS verified), Unconjugated
• Artikelnummer: ABS-GHR-H5222-1MG
• Hersteller Artikelnummer: GHR-H5222-1mg
• Alternativnummer: ABS-GHR-H5222-1MG
• Hersteller: AcroBiosystems
• Wirt: Human
• Kategorie: Proteine/Peptide
• Spezies Reaktivität: Human
• Konjugation: Unconjugated

Produktbeschreibung

Growth hormone receptor (GHR) is also known as somatotropin receptor, growth hormonebinding protein (GHBR), which belongs to the type I cytokine receptor family or Type 1 subfamily. GHR contains one fibronectin typeIII domain. GHR / GHBR is expressed in various tissues with high expression in liver and skeletal muscle. The soluble form (GHBP) is produced by phorbol esterpromoted proteolytic cleavage at the cell surface (shedding) by ADAM17/TACE. GHR is receptor for pituitary gland growth hormone involved in regulating postnatal body growth. On ligand binding, couples to the JAK2/STAT5 pathway. The soluble form (GHBP) acts as a reservoir of growth hormone in plasma and may be a modulator/inhibitor of GH signaling. - Proteine/Peptide

Produkteigenschaften

• Molekulargewicht: 29.6 kDa
• Tag: C-10*His
• NCBI: 10912
• Puffer: PBS, pH7.4
• Reinheit: 95%
• Formulierung: Powder
• Target-Kategorie: Growth Hormone R

Bilder

Immobilized Human GH, premium grade (Cat. No. GH1-H4118) at 2 µg/mL (100 µL/well) can bind Human GHR, His Tag (Cat. No. GHR-H5222) with a linear range of 0.2-3 ng/mL (QC tested).

Human GHR, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.