Biotinylated Human Growth Hormone R Protein, Fc,Avitag(TM) (MALS verified)

Artikelnummer: ABS-GHR-H82F3-25UG
Artikelname: Biotinylated Human Growth Hormone R Protein, Fc,Avitag(TM) (MALS verified)
Artikelnummer: ABS-GHR-H82F3-25UG
Hersteller Artikelnummer: GHR-H82F3-25ug
Alternativnummer: ABS-GHR-H82F3-25UG
Hersteller: AcroBiosystems
Wirt: Human
Kategorie: Proteine/Peptide
Spezies Reaktivität: Human
Konjugation: Biotin
Growth hormone receptor (GHR) is also known as somatotropin receptor, growth hormonebinding protein (GHBR), which belongs to the type I cytokine receptor family or Type 1 subfamily. GHR contains one fibronectin typeIII domain. GHR / GHBR is expressed in various tissues with high expression in liver and skeletal muscle. The soluble form (GHBP) is produced by phorbol esterpromoted proteolytic cleavage at the cell surface (shedding) by ADAM17/TACE. GHR is receptor for pituitary gland growth hormone involved in regulating postnatal body growth. On ligand binding, couples to the JAK2/STAT5 pathway. The soluble form (GHBP) acts as a reservoir of growth hormone in plasma and may be a modulator/inhibitor of GH signaling. - Proteine/Peptide
Molekulargewicht: 55 kDa
Tag: C-Fc & C-Avi
NCBI: 10912
Puffer: PBS, pH7.4
Reinheit: 90%
Formulierung: Powder
Target-Kategorie: Growth Hormone R
Immobilized Human GH, premium grade (Cat. No. GH1-H4118) at 1 µg/mL (100 µL/well) can bind Biotinylated Human Growth Hormone R Protein, Fc,Avitag (Cat. No. GHR-H82F3) with a linear range of 0.2-8 ng/mL (QC tested).
Biotinylated Human Growth Hormone R Protein, Fc,Avitag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.