Biotinylated Human GITR Ligand / TNFSF18 Protein, Avitag(TM),Fc Tag

Artikelnummer: ABS-GIL-H82F8-25UG
Artikelname: Biotinylated Human GITR Ligand / TNFSF18 Protein, Avitag(TM),Fc Tag
Artikelnummer: ABS-GIL-H82F8-25UG
Hersteller Artikelnummer: GIL-H82F8-25ug
Alternativnummer: ABS-GIL-H82F8-25UG
Hersteller: AcroBiosystems
Wirt: Human
Kategorie: Proteine/Peptide
Spezies Reaktivität: Human
Konjugation: Biotin
Tumor necrosis factor ligand superfamily member 18 (TNFSF18) is also known as Glucocorticoid induced TNFrelated ligand (GITRL or GITR Ligand), Activation inducible TNF related ligand (AITRL), which belongs to the tumor necrosis factor family. TNFSF18 is expressed at high levels in the small intestine, ovary, testis, kidney and endothelial cells. TNFSF18 / GITRL is upregulated after stimulation by bacterial lipopolysaccharides (LPS). TNFSF18 Can function as costimulator and lower the threshold for Tcell activation and Tcell proliferation. TNFSF18 / GITR Ligand is important for interactions between activated Tlymphocytes and endothelial cells. TNFSF18 also mediates activation of NFkappaB. - Proteine/Peptide
Molekulargewicht: 43.5 kDa
Tag: N-Avi & N-Fc
NCBI: 69319
Puffer: Tris with Glycine, Arginine and NaCl, pH7.5
Reinheit: 95%
Formulierung: Powder
Target-Kategorie: GITR Ligand
Immobilized Human GITR, Fc Tag (Cat. No. GIR-H5254) at 2 µg/mL (100 µL/well) can bind Biotinylated Human GITR Ligand, Avitag,Fc Tag (Cat. No. GIL-H82F8) with a linear range of 4-63 ng/mL (QC tested).
Biotinylated Human GITR Ligand, Avitag,Fc Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.